Phlebolymphology N°100

Changes in clinical manifestations and biophysical properties of the great saphenous vein in transient premenstrual phlebopathy after 12 months’ treatment with micronized purified flavonoid fraction

Yuri T. TSUKANOV, PhD, Aleksandr NICOLAICHUK, MD Department of Surgery and Urology, Omsk State Medical University, Omsk, Russia Abstract Aim. To study clinical manifestations and biophysical properties of the great saphenous vein (GSV) in 42 women with transient premenstrual phlebopathy (TPP) after 12 months of micronized purified flavonoid fraction (MPFF) treatment (1000 mg/day) and to compare GSV diameters measured in 84 legs before 10:00 and after 18:00. In 12 months the number of women with leg heaviness and swelling decreased to 2 (4.8%). The interphase gradient of the circumference (a difference between the circumferences during the secretory and menstrual phases)…

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Management of small saphenous vein varices with perspectives from a recent meta-analysis and recommendations

Nicolas NEAUME Clinique Pasteur, 45 avenue de Lombez, 31076 Toulouse, France Abstract The methods of treating varicose veins have been constantly evolving over the past 20 years, leaving a prominent place today for endovenous techniques, with conventional surgery being gradually abandoned. The modern treatment of varicose veins of the lower-limbs is performed either by tumescent endovenous thermal techniques (laser, radiofrequency, steam) or by nonthermal nontumescent techniques (ultrasound-guided foam sclerotherapy, glue cyanoacrylate, mechanochemical endovenous ablation). The introduction of minimally invasive endovenous ablation techniques (thermal and nonthermal techniques) are associated with several advantages, including minimally invasive, immediate discharge and ambulation, faster recovery,…

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Management of chronic venous insufficiency patients presenting an axial deep reflux in isolation orcombined with iliac vein obstruction

Yuji HOSHINO, MD Section of Vascular Surgery. Fukuoka Sanno Hospital, Japan Abstract The pathology of chronic deep venous incompetence often involves postthrombotic syndrome, secondary to an episode of deep venous thrombosis. Obstruction of the iliac vein and valve incompetence of the femoral/popliteal veins produce symptoms caused by the resulting chronic venous hypertension in the legs. The clinical symptoms are common symptoms of chronic venous insufficiency: varicose vein formation, swelling of the lower-limbs, heaviness, venous claudication, stasis dermatitis/pigmentation, and ulceration; these are generally severe and refractory in cases of deep venous incompetence. Diagnosis and assessment are based on ultrasonography, similarly to…

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Long-haul travel venous thromboembolism – an update

Sarah ONIDA, Alun H. DAVIE Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College Abstract Venous thromboembolism (VTE) describes obstructive presentations of deep venous disease, including deep vein thrombosis and pulmonary embolism, which, together, affect up to half a million people in Europe every year. VTE is also the single, most common cause of preventable hospital-acquired mortality; furthermore, up to 50% of individuals with deep vein thrombosis develop the postthrombotic syndrome, with its significant impact on quality of life and a considerable economic burden. Immobility is amongst the most important recognized risk factors for VTE. Long-haul travel,…

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Pathophysiology of edema in patients with chronic venous insufficiency

Mohamed K. KAMEL, John BLEBEA Department of Surgery, College of Medicine , Central Michigan University, Saginaw, MI, USA Abstract The prevalence of chronic venous insufficiency and its associated health care costs have been greatly underestimated for a long period of time. Many patients suffering from chronic venous insufficiency either present with or have associated lower-limb edema. The main pathophysiological mechanisms of edema formation in such patients include increased capillary hydrostatic pressures secondary to valvular insufficiency or venous obstruction. In addition, there is increased capillary permeability due to associated inflammatory reactions that subsequently lead to leakage of protein-rich fluid into the…

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Phlebolymphology N°100 – Editorial

Dear Readers, In this new issue of Phlebolymphology, Mohamed K. KAMEL and John BLEBEA (USA) present the anatomic, hemodynamic, and main pathophysiological mechanisms of lower-limb edema formation in patients with chronic venous insuffiency. Sarah ONIDA and Alun H. DAVIES (UK) summarize the existing evidence on long-haul travel and venous thromboembolism, while considering the pathophysiology underlying the development of thrombotic events, factors increasing risk, and what conservative and pharmacological measures can be taken to reduce the venous thromboembolism risk. Yuji HOSHINO (Japan) discuss the management of chronic venous insufficiency patients presenting an axial deep reflux in isolation or combined with iliac…

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Phlebolymphology N°100 (Vol 27 – N°1 – 2020)

EDITORIAL Editorial PHLEBOLOGY Pathophysiology of edema in patients with chronic venous insufficiency Mohamed K. KAMEL, John BLEBEA (USA) Phlebolymphology – 2020 ; 27 (1): 3 Long-haul travel venous thromboembolism – an update Sarah ONIDA, Alun H. DAVIES (UK) Phlebolymphology – 2020 ; 27 (1): 11 Management of chronic venous insufficiency patients presenting an axial deep reflux in isolation or combined with iliac vein obstruction Yuji HOSHINO (Japan) Phlebolymphology – 2020 ; 27 (1): 17 Management of small saphenous vein varices with perspectives from a recent meta-analysis and recommendations Nicolas NEAUME (France) Phlebolymphology – 2020 ; 27 (1): 28 Changes in…

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